Author

J. Briggs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Approach:Bayesian inference· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1

Frequent Co-Authors

A. Gresch· 1 shared A. Koehler· 1 shared A. von Kügelgen· 1 shared A. Yeroslaviz· 1 shared B. Hampoelz· 1 shared C. Beecks· 1 shared D. Castano-Diez· 1 shared D. Morado· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPhysiology

A. Gresch

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

In-cell structure and snapshots of copia retrotransposons in intact tissue by cryo-electron tomography

S. Klumpe, K. A. Senti, F. Beck, J. Sachweh, B. Hampoelz, P. Ronchi, A. Yeroslaviz, J. Briggs, J. Brennecke, M. Beck, J. M. Plitzko

This study uses cryo-ET to visualize copia retrotransposon structure in Drosophila cells, revealing nuclear clustering and size selection during gametogenesis.

Cell · Apr 1, 2025Peer-reviewedBiophysics

Resolving spatiotemporal electrical signaling within the islet via CMOS microelectrode arrays

A. Gresch, J. D. Huewel, J. Briggs, T. Berger, R. Koch, T. Deickert, C. Beecks, R. K. Benninger, M. Duefer

This paper uses CMOS microelectrode arrays to study electrical signal propagation in mouse islets, finding glucose-dependent changes in wave velocity and identifying a subpopulation of active cells.

bioRxiv · Oct 24, 2023Physiology

A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0

J. Zivanov, J. Oton, Z. Ke, A. von Kügelgen, E. Pyle, K. Qu, D. Morado, D. Castano-Diez, G. Zanetti, T. Bharat, J. Briggs, S. Scheres

The paper introduces a Bayesian method for improving cryo-ET data analysis in RELION-4.0, enabling higher-resolution structure determination from multiple particles.

bioRxiv · Feb 28, 2022Biophysics

Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers

W. Wan, M. Clarke, M. Norris, L. Kolesnikova, A. Koehler, Z. Bornholdt, S. Becker, E. O. Saphire, J. Briggs

The paper determines the structure of VP40 matrix layers in Ebola and Marburg virus-like particles, revealing they are locally ordered assemblies of VP40 dimers forming 2D lattices.

bioRxiv · May 25, 2020Microbiology