Author

J. Espadas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 2 Organism:Arabidopsis· 1 Approach:comparative / phylogenetic analysis· 1 Assay:cryo-EM· 1 Organism:Drosophila· 1 Organism:human· 1

Frequent Co-Authors

A. Roux· 3 shared A. Velasco del Olmo· 2 shared B. Ibarra· 2 shared R. Bocanegra· 2 shared A. Colom· 1 shared A. Daga· 1 shared A. Escalada· 1 shared A. Merino· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersEvolutionary Biology

A. Roux

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Evolutionarily conserved principles of ESCRT-III-mediated membrane remodelling revealed by a two-subunit Asgard archaeal system

D. P. Souza, J. Espadas, S. Chaaban, E. R. R. Moody, T. Hatano, M. Balasubramanian, T. A. Williams, A. Roux, B. Baum

The paper identifies evolutionarily conserved principles of ESCRT-III-mediated membrane remodeling using an Asgard archaeal two-subunit system, showing homology to eukaryotic ESCRT-IIIB and IIIA.

bioRxiv · Jul 1, 2024Evolutionary Biology

Mechanism for Vipp1 spiral formation, ring biogenesis and membrane repair

S. Naskar, A. Merino, J. Espadas, J. Singh, A. Roux, A. Colom, H. H. Low

The paper investigates how Vipp1 polymerizes into planar sheets and spirals on membranes, revealing geometric transitions that may inform ESCRT-III filament behavior.

bioRxiv · Sep 26, 2023Microbiology

Membrane remodeling properties of the Parkinson's disease protein LRRK2

X. Wang, J. Espadas, Y. Wu, S. Cai, J. Ge, L. Shao, A. Roux, P. De Camilli

This study shows that LRRK2 binds and remodels lipid membranes, suggesting its role in membrane dynamics and signaling.

bioRxiv · Aug 10, 2022Cell Biology

GTP and lipids control self-assembly and functional promiscuity of Dynamin2 molecular machinery

J. Espadas, R. Bocanegra, J. M. Martinez Galvez, E. Largo, S. Banos-Mateos, P. Arrasate, J. Ormaetxea Guisasola, A. Velasco del Olmo, J. Vera Lillo, B. Ibarra, A. V. Shnyrova, V. A. Frolov

This study investigates how GTP and lipids regulate the self-assembly and functional versatility of Dynamin2 during membrane remodeling processes.

bioRxiv · Mar 15, 2021 · PreprintBiophysics

Dynamic constriction and fission of ER membranes by reticulon

J. Espadas, D. Pendin, R. Bocanegra, A. Escalada, G. Misticoni, T. Trevisan, A. Velasco del Olmo, S. Bova, B. Ibarra, P. Kuzmin, A. Shnyrova, V. Frolov, A. Daga

This study identifies reticulon as a key protein driving ER membrane fission and shows its dynamic balance with fusion in Drosophila.

bioRxiv · Nov 17, 2018 · PreprintCell Biology