Author

J. Insua-Rodriguez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell-cell communication· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. Pein· 3 shared J. Meier· 2 shared T. Hongu· 2 shared T. Oskarsson· 2 shared A. Descot· 1 shared A. Markaryan· 1 shared A. Riedel· 1 shared A. Schneeweiss· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

M. Pein

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 20, 2021

Pre-neoplastic stromal cells drive BRCA1-mediated breast tumorigenesis

K. Nee, D. Ma, Q. H. Nguyen…·K. Kessenbrock

The paper shows pre-neoplastic stromal cells promote BRCA1-driven breast cancer by inducing epithelial proliferation and altering differentiation.

DOI 10.1101/2021.10.20.465221

𝕏 PostBluesky

Cancer BiologybioRxivMar 30, 2021

Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs

T. Hongu, M. Pein, J. Insua-Rodriguez…·T. Oskarsson

The paper identifies four secreted factors from metastasis-associated endothelial cells that promote breast cancer metastasis by enhancing cancer cell stemness and survival, with perivascular macrophages mediating this effect via the TNC-TLR4 axis.

DOI 10.1038/s43018-022-00353-6

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivFeb 11, 2019

CXCR3-expressing metastasis-initiating cells induce and exploit a fibroblast niche in the lungs to fuel metastatic colonization

M. Pein, J. Insua-Rodriguez, J. Meier…·T. Oskarsson

This study identifies CXCR3-expressing breast cancer cells that induce fibroblast production of CXCL9/10 via IL-1 and JNK signaling, promoting metastatic colonization in the lungs.

DOI 10.1038/s41467-020-15188-x

mousebulk RNA-seq

𝕏 PostBluesky