J. Kalinowski

Glycerol degradation in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius involves an unusual glycerol-3-phosphate dehydrogenase

This study identifies an unusual glycerol-3-phosphate dehydrogenase in Sulfolobus acidocaldarius involved in glycerol degradation, showing its essential role in growth on glycerol.

A rolling circle-replicating plasmid as an Inovirus phage satellite

The paper describes a novel Inovirus phage, Dolos, and its associated rolling circle-replicating plasmid pDolos, which hijacks phage functions to disseminate genetic material.

Deletion of SMC renders FtsK essential in Corynebacterium glutamicum

This paper shows that in Corynebacterium glutamicum, deletion of SMC makes FtsK essential for chromosome segregation, as FtsK compensates for SMC loss by extending its activity at the septum.

Inducible mucosa-like differentiation of head and neck cancer cells drives the epigenetically determined loss of cell malignancy

This study shows that HNSCC cells can differentiate into non-malignant cells, losing their tumor-initiating potential and expressing KRT17, suggesting differentiation as a therapeutic target.

Gene losses resulting in specialized metabolism in the earliest divergent symbiotic Frankia clade can be linked to its low saprotrophic capabilities

The paper investigates nitrogen export in Frankia cluster-2 strains and identifies gene losses linked to specialized metabolism and reduced saprotrophic capabilities.

Uncoupling of the Diurnal Growth Program by Artificial Genome Relaxation in Synechocystis sp. PCC 6803

The paper manipulates DNA supercoiling in Synechocystis sp. PCC 6803 using CRISPRi and TopoI overexpression, revealing its role in diurnal gene regulation and growth.

A persistent giant algal virus, with a unique morphology, encodes an unprecedented number of genes involved in energy metabolism

This paper describes a giant algal virus with a unique morphology and an unprecedented number of genes involved in energy metabolism, including enzymes from the TCA cycle and β-oxidation pathway.

Discovery of interaction-related sRNAs and their targets in the Brachypodium distachyon and Magnaporthe oryzae pathosystem

This study identifies bidirectional small RNA (sRNA) effectors and their targets between the rice blast fungus Magnaporthe oryzae and the grass Brachypodium distachyon, providing experimental evidence for cross-kingdom RNA interference (ckRNAi).

Host-induced gene silencing involves Arabidopsis ESCRT-III pathway for the transfer of dsRNA-derived siRNA

This study identifies the Arabidopsis ESCRT-III pathway as essential for transferring dsRNA-derived siRNAs between host and fungal cells during host-induced gene silencing.

Phytoplankton consortia as a blueprint for mutually beneficial eukaryote-bacteria ecosystems: Biocoenosis of Botryococcus consortia

The paper analyzes the microbial consortium of Botryococcus phytoplankton, revealing functional interactions between eukaryotic and bacterial members and proposing a model for synthetic beneficial ecosystems.

A universal method for gene expression engineering

This paper introduces GeneEE, a method for creating artificial gene expression systems that works across six bacterial species and Bakers yeast.

The MarR-type regulator MalR is involved in stress-responsive cell envelope remodeling in Corynebacterium glutamicum

This study identifies MalR as a regulator of stress-responsive cell envelope remodeling in C. glutamicum through genome-wide binding analysis and transcriptome profiling.

RAD sequencing and a hybrid Antarctic fur seal genome assembly reveal rapidly decaying linkage disequilibrium, global population structure and evidence for inbreeding

Novel chromosome organization pattern in actinomycetales-overlapping replication cycles combined with diploidy

The paper investigates chromosome organization in Corynebacterium glutamicum, finding diploidy and overlapping replication cycles with simultaneous origin initiation.