Author

J. Olzmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Approach:genetic perturbation / CRISPR· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

K. K. Deol· 2 shared S. J. Dixon· 2 shared A. He· 1 shared A. K. Amaya· 1 shared A. Tarangelo· 1 shared C. Riepe· 1 shared E. Lingeman· 1 shared J. E. Corn· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCell Biology

K. K. Deol

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Author profile →

4 papers

Recent·Most cited

Small molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states

C. Riepe, M. Wachalska, K. K. Deol, A. K. Amaya, M. H. Porteus, J. Olzmann, R. R. Kopito

The paper identifies molecular machinery underlying CFTR-F508del ERAD and shows correctors stabilize RNF5-resistant folding states.

Molecular Biology of the Cell · Feb 1, 2024Peer-reviewedCell Biology

A Cell Cycle-Dependent Ferroptosis Sensitivity Switch Governed by EMP2

J. Rodencal, N. Kim, V. Li, A. He, M. Lange, J. He, A. Tarangelo, Z. T. Schafer, J. Olzmann, J. Sage, J. Z. Long, S. J. Dixon

The paper shows cell cycle arrest increases sensitivity to GPX4 inhibitor-induced ferroptosis via elevated oxidizable phospholipids and reduced EMP2 expression.

bioRxiv · Jul 19, 2023 · PreprintCancer Biology

Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability in cancer

Z. Li, L. Ferguson, K. K. Deol, M. A. Roberts, L. Magtanong, M. C. Bassik, S. J. Dixon, N. Ingolia, J. Olzmann

The paper identifies LRP8 as a ferroptosis resistance factor in cancer, showing that its loss causes ribosome stalling during GPX4 translation, exposing a vulnerability in cancer cells.

bioRxiv · Apr 11, 2022Cancer Biology

A genome-wide screen for ER autophagy highlights key roles of mitochondrial metabolism and ER- resident UFMylation

J. R. Liang, E. Lingeman, T. Luong, S. Ahmed, T. Nguyen, J. Olzmann, J. E. Corn

The paper identifies 200 factors involved in human ER-phagy through CRISPRi screening and reveals mitochondrial metabolism and ER-resident UFMylation as key regulators.

bioRxiv · Feb 25, 2019Cell Biology