Author

S. A. Khader

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Organism:rat· 2

Frequent Co-Authors

M. Ahmed· 4 shared B. Singh· 3 shared D. K. Singh· 3 shared D. Kaushal· 3 shared J. Cole· 3 shared A. Swain· 2 shared B. A. Rosa· 2 shared E. Esaulova· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersImmunology

M. Ahmed

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Myeloid cell interferon responses correlate with clearance of SARS-CoV-2

D. K. Singh, E. Aladyeva, S. Das, B. Singh, E. Esaulova, A. Swain, M. Ahmed, J. Cole, C. Moodley, S. Mehra, L. Schlesinger, M. Artyomov, S. A. Khader, D. Kaushal

This study uses longitudinal single-cell RNA sequencing in rhesus macaques to show that myeloid cell interferon responses correlate with SARS-CoV-2 clearance.

bioRxiv · Jun 28, 2021Immunology

Lung epithelial signaling mediates early vaccine-induced CD4+ T cell activation and Mtb control

S. Das, N. D. Marin, E. Esaulova, M. Ahmed, A. Swain, B. A. Rosa, M. Mitreva, J. Rangel-Moreno, M. Netea, L. B. Barreiro, M. Divangahi, M. Artyomov, D. Kaushal, S. A. Khader

This study identifies lung epithelial signaling as critical for early vaccine-induced CD4+ T cell activation and Mtb control in BCG vaccinated hosts.

bioRxiv · Jun 3, 2021Immunology

Mitochondrial cyclophilin D promotes disease tolerance by licensing NK cell development and IL-22 production against influenza virus

J. Downey, H. E. Randolph, E. Pernet, K. A. Tran, S. A. Khader, I. L. King, L. B. Barriero, M. Divangahi

This study shows that mitochondrial cyclophilin D promotes disease tolerance against influenza virus by supporting NK cell development and IL-22 production, reducing lung damage.

bioRxiv · May 28, 2021Immunology

IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection

B. A. Rosa, M. Ahmed, D. K. Singh, J. A. Choreno-Parra, J. Cole, L. A. Jimenez-Alvarez, T. S. Rodriguez-Reyna, B. Singh, O. Golzalez, R. Carrion, L. S. Schlesinger, J. Martin, J. Zuniga, M. Mitreva, S. A. Khader, D. Kaushal

This study identifies transcriptional signatures of IFN signaling and neutrophil degranulation in SARS-CoV-2 infected rhesus macaques and humans, highlighting age-related differences and shared pathways with tuberculosis.

bioRxiv · Aug 6, 2020Immunology

SARS-CoV-2 infection leads to acute infection with dynamic cellular and inflammatory flux in the lung that varies across nonhuman primate species

D. K. Singh, S. R. Ganatra, B. Singh, J. Cole, K. J. Alfson, E. Clemmons, M. Gazi, O. Gonzalez, R. Escabedo, T.-H. Lee, A. Chatterjee, Y. Goez-Gazi, R. Sharan, R. Thippeshappa, M. Gough, , M

This study compares SARS-CoV-2 infection in three nonhuman primate species, showing varied disease progression and immune responses.

bioRxiv · Jun 5, 2020Immunology

Cryptococcus neoformans evades pulmonary immunity by modulating xylose precursor transport

L. X. Li, C. R. Hole, J. Rangel-Moreno, S. A. Khader, T. L. Doering

This study shows that Cryptococcus neoformans evades pulmonary immunity by modulating xylose precursor transport, leading to altered immune responses and iBALT formation.

bioRxiv · May 11, 2020Microbiology