Author

J. Rowley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Natarajan· 2 shared S. Kumar· 2 shared A. A. de Cubas· 1 shared A. C. Macke· 1 shared A. Eiken· 1 shared A. Kalluchi· 1 shared A. Krishna· 1 shared A. L. Smith· 1 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCancer Biology

A. Natarajan

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Author profile →

4 papers

Recent·Most cited

Novel spirocyclic dimer, SpiD3, targets chronic lymphocytic leukemia survival pathways with potent preclinical effects

A. Eiken, A. L. Smith, S. A. Skupa, E. Schmitz, S. Rana, S. Singh, S. Kumar, J. R. Mallareddy, A. A. de Cubas, A. Krishna, A. Kalluchi, J. Rowley, C. R. D'Angelo, M. A. Lunning, R. G. Bociek, , D. ElGamal

This paper evaluates SpiD3, a novel spirocyclic dimer, showing potent anti-leukemic effects in CLL cells, including resistance to ibrutinib, by targeting NF-κB signaling and the UPR.

bioRxiv · Jan 31, 2024Cancer Biology

Searching for Structure: Characterizing the Protein Conformational Landscape with Clustering-based Algorithms

A. C. Macke, J. E. Stump, M. S. Kelly, J. Rowley, V. Herath, S. Mullen, R. I. Dima

This paper introduces StELa, a clustering method that identifies protein conformational minima more effectively than existing methods like GROMOS and CATS.

bioRxiv · Sep 13, 2023Biophysics

Characterization of m6A modifiers and RNA modifications in uterine fibroids

J. W. George, R. Cancino, J. L. G. Miller, F. Qiu, Q. Lin, J. Rowley, V. Chennathukuzhi, J. S. Davis

This study characterizes m6A modifiers and RNA modifications in uterine fibroids using RNA-seq, RT-qPCR, and mass spectrometry, finding limited differential expression despite heterogeneity.

bioRxiv · Aug 7, 2023Cancer Biology

GD2 and its biosynthetic enzyme GD3 synthase promote tumorigenesis in prostate cancer by regulating cancer stem cell behavior

A. M. Bhat, B. C. Mohapatra, H. Luan, I. Mushtaq, S. Chakraborty, S. Kumar, W. Wu, B. Nolan, S. Dutta, M. D. Stock, M. Schott, J. L. Meza, S. M. Lele, M.-F. Lin, L. M. Cook, , H. Band

This study shows GD2 and its biosynthetic enzyme GD3S promote prostate cancer tumorigenesis by maintaining cancer stem cells and EMT markers.

bioRxiv · Mar 18, 2023Cancer Biology