F. Qiu

CDC5L surveils cellular stress responses and stress granule formation through transcriptional repression

This study identifies CDC5L as a transcriptional repressor that prevents spontaneous stress granule formation by suppressing PERK-eIF2 signaling.

Characterization of m6A modifiers and RNA modifications in uterine fibroids

This study characterizes m6A modifiers and RNA modifications in uterine fibroids using RNA-seq, RT-qPCR, and mass spectrometry, finding limited differential expression despite heterogeneity.

Structural insights into Rad18 targeting by the SLF1 BRCT domains

The paper presents the crystal structure of SLF1tBRCT bound to Rad18 peptide, revealing mechanisms of Rad18 recognition and BRCT-mediated complex assembly.

FGFR1 governs iron metabolism via regulating post-translational modification of IRP2 in prostate cancer cells

This study shows FGFR1 promotes prostate cancer by enhancing iron metabolism through regulation of IRP2 post-translational modification and TFR1 expression.

Expansion and Adaptive Evolution of the mTERF Gene Family in Plants

The paper analyzes the expansion and adaptive evolution of mTERF genes in plants, finding that M-class mTERF genes expanded via tandem duplication and evolved rapidly with positive selection in nucleic acid-binding sites.

Deep oncopanel sequencing reveals fixation time- and within block position-dependent quality degradation in FFPE processed samples

This study identifies FFPE processing errors in oncology panel sequencing by analyzing variants from technical artifacts in FFPE samples with varying fixation times and block positions.

Recombinant SARS-CoV-2 RBD molecule with a T helper epitope as a built in adjuvant induces strong neutralization antibody response

This study develops a recombinant SARS-CoV-2 RBD molecule fused with a T helper epitope as an adjuvant, showing strong neutralizing antibody response in mice.

Microbubble-Mediated Cavitation Promotes Apoptosis and Suppresses Invasion in AsPC-1 Cells

This study shows that microbubble-mediated cavitation induces apoptosis and reduces invasion in AsPC-1 cancer cells through increased calcium, cleaved Caspase-3, BAX, and decreased Bcl-2, HIF-1, and Vimentin.

Lineage Functional Types (LFTs): Characterizing functional diversity to enhance the representation of ecological behavior in Earth System Models

The paper develops lineage-based functional types (LFTs) to improve Earth System Models by incorporating phylogenetic relatedness and trait variation in grasses.