S. Rana

This study shows ivermectin reduces SARS-CoV-2 viral burden in vitro but at concentrations that also cause cytotoxicity, suggesting its antiviral effect may be due to nonspecific membrane perturbation rather than specific antiviral activity.

The paper identifies KRAS-induced COX-2 as a driver of immunotherapy resistance in lung cancer through CRISPR/Cas9 screening and shows targeting COX-2 enhances immune checkpoint blockade efficacy.

This study shows that SUMOylation of SifA in Salmonella Typhimurium is essential for intracellular survival by modulating lysosomal function and SIF formation.

The paper identifies a gene, AtSUC8, whose allelic differences contribute to increased productivity in mixed Arabidopsis thaliana genotypes by affecting root growth sensitivity to substrate pH.

KRASG12C inhibition enhances anti-tumour immunity in immunogenic lung cancers by upregulating interferon signaling through Myc repression, but only synergizes with immune checkpoint blockade in highly immunogenic models.

This study combines morphological and transcriptomic analyses to show brassinosteroid signaling regulates cell division orientation and anisotropic expansion in Arabidopsis roots, with non-cell-autonomous effects on root anatomy.

The paper optimises an imaging mass cytometry workflow to study TME remodelling in mouse models after KRAS G12C inhibitor treatment.

This paper develops an immunogenic mouse model of KRAS-mutant lung cancer that responds to immunotherapy and reveals immune responses target endogenous retroviral antigens rather than neoantigens.

This study shows that miR-15a regulates SMPD1 in endothelial cells, affecting angiogenesis and tumor growth in response to radiation.

This study identifies miR-451a as a regulator of colorectal cancer radiosensitivity, showing it inhibits proliferation and enhances radiation response.