D. Bauer

Exploring the PET in vivo generator 134Ce as a theranostic match for 225Ac

This paper compares 225Ac and 134Ce-labeled tracers in cancer models to assess their suitability as a theranostic pair, finding that 134Ce's PET imaging is limited by daughter nuclide redistribution.

Direct delivery of stabilized Cas-embedded base editors achieves efficient and accurate editing of clinically relevant targets

This study develops stabilized Cas-embedded base editors (sCE_CBEs) that enable efficient and accurate C-to-T editing with minimal off-target effects in hematopoietic stem and progenitor cells.

Evolutionary analyses of gene expression divergence in Panicum hallii: exploring constitutive and plastic responses using reciprocal transplants

This study examines gene expression divergence in Panicum hallii using reciprocal transplants, finding constitutive divergence but no plastic responses, and links divergence to cis-regulatory factors.

Radiances of Cerenkov-Emitting Isotopes on the IVIS

The paper presents the largest experimental dataset of Cerenkov-emitting isotopes measured using IVIS, providing normalized radiance values for 21 isotopes across various emissions.

Ocean currents drive the worldwide colonization of the most widespread marine plant, eelgrass (Zostera marina)

The paper reconstructs the colonization history of eelgrass using genomic data, showing trans-Pacific currents drove its spread and Atlantic populations arrived more recently with lower genetic diversity.

Genome evolution and transcriptome plasticity associated with adaptation to monocot and eudicot plants in Colletotrichum fungi

This study analyzes genome and transcriptome data from 30 Colletotrichum species to show evolutionary adaptations to monocot and eudicot hosts, including gene expansion and expression changes.

Broad human and animal coronavirus neutralisation by SARS-CoV-2 S2-targeted vaccination

This study shows that SARS-CoV-2 S2-targeted vaccination induces broad neutralizing antibodies against multiple coronaviruses and provides better protection than homologous boosting.

Genetic determinants of endophytism in the Arabidopsis root mycobiome

The paper identifies genetic factors associated with endophytism in Arabidopsis root fungi, showing specific gene families linked to aggressive colonization and plant health.

Novel insights into joint estimations of demography, mutation rate, and selection using UV sex chromosomes

This study examines how anisogamy influences genetic variation in moss using UV sex chromosomes, finding sex-biased mutation and selection but no model explaining observed diversity ratios.

Consensus tandem tetratricopeptide repeat proteins are complex superhelical nanosprings

This study investigates the mechanical properties of consensus-designed tetratricopeptide repeats (CTPRs) using single-molecule techniques, revealing their spring-like behavior and superhelical structure.

Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains

This study compares antibody cross-reactivity between SARS-CoV-2 B.1.1.7 and parental strains, finding reduced recognition and neutralization of older variants after B.1.1.7 infection.

Intra-ocular dendritic cells are increased in HLA-B27 associated acute anterior uveitis

The paper characterizes intraocular leukocyte infiltration in HLA-B27-associated uveitis using scRNA-seq, flow cytometry, and proteomics, revealing a unique dendritic cell infiltration pattern.

Analysis of Biological Noise in an Organelle Size Control System

The paper analyzes biological noise in flagellar length control in Chlamydomonas, showing cell-to-cell and within-cell variation and linking it to homeostatic mechanisms and tubulin dynamics.

Bioorthogonal protein-DNA conjugation methods for force spectroscopy

This paper introduces bioorthogonal methods for site-specific DNA-protein conjugation to improve force spectroscopy techniques, expanding the range of proteins that can be studied.

The inhibitory effects of butein on cell proliferation and TNF-α-induced CCL2 release in racially different triple negative breast cancer cells

This study shows butein reduces cell proliferation and CCL2 release in TNBC cells, with stronger effects in African American-derived cells than in Caucasian-derived cells.

Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias

This study identifies a synthetic lethal interaction between Wnt pathway activation and asparaginase in drug-resistant leukemias, showing that Wnt/STOP signaling can sensitize resistant cells to asparaginase.

Ankyrin-1 gene exhibits allelic heterogeneity in conferring protection against malaria

This study identifies two Ank-1 mutations in mice that confer differing protection against Plasmodium chabaudi infections, demonstrating allelic heterogeneity in ankyrin-1's role in malaria resistance.

The Sequence of 1504 Mutants in the Model Rice Variety Kitaake Facilitates Rapid Functional Genomic Studies

The paper sequenced 1,504 mutant lines in the rice variety Kitaake and established a database to enable rapid functional genomic studies.