Author

J. Schoen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2 Physiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:rat· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

D. Hoffmann· 5 shared M. Beer· 4 shared K. Wernike· 3 shared L. Ulrich· 3 shared N. Roth· 3 shared S. Rauch· 3 shared A. Aebischer· 2 shared A. Dorhoi· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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5 shared papersMicrobiology

D. Hoffmann

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Assessment of Immunogenicity and Efficacy of CV0501 mRNA-based Omicron COVID-19 Vaccination in Small Animal Models

N. Roth, J. Gergen, K. Kovacikova, S. Mueller, L. Ulrich, J. Schoen, N. J. Halwe, C. Fricke, B. Corleis, A. Dorhoi, D. Hoffmann, M. Beer, D. Maione, B. W. Petsch, S. Rauch

This paper evaluates the immunogenicity and efficacy of a bivalent mRNA vaccine CV0501 against Omicron subvariants in animal models, showing robust neutralizing antibodies and reduced viral loads.

bioRxiv · Jan 4, 2023Immunology

A fungal endophyte-generated nucleoside signal regulates host cell death and promotes root colonization

N. Dunken, H. Widmer, G. U. Balcke, H. Straube, G. Langen, N. M. Charura, P. Saake, C. De Quattro, J. Schoen, H. Roevenich, S. Wawra, A. Djamei, M. D. Zurbriggen, A. F. Tissier, C.-P. F. Witte, A. Zuccaro

This study identifies fungal enzymes that produce a metabolite triggering plant cell death, which is essential for fungal colonization of roots.

bioRxiv · Mar 11, 2022Plant Biology

Serological screening in wild ruminants in Germany, 2021/22: No evidence of SARS-CoV-2, bluetongue virus or pestivirus spread but high seroprevalences against Schmallenberg virus

K. Wernike, L. Fischer, M. Holsteg, A. Aebischer, A. Petrov, K. Marquart, U. Schotte, J. Schoen, D. Hoffmann, S. Hechinger, A. Neubauer-Juric, J. Blicke, T. C. Mettenleiter, M. Beer

The paper serologically screens wild ruminants in Germany for SARS-CoV-2, bluetongue virus, pestivirus, and Schmallenberg virus, finding no evidence of spread but high seroprevalence against Schmallenberg virus and potential cross-reactivity with SARS-CoV-2.

bioRxiv · Feb 21, 2022Microbiology

Optimised non-coding regions of mRNA SARS-CoV-2 vaccine CV2CoV improves homogeneous and heterogenous neutralising antibody responses

N. Roth, J. Schoen, D. Hoffmann, M. Thran, A. Thess, S. O. Mueller, B. Petsch, S. Rauch

This study compares two mRNA vaccines, CVnCoV and CV2CoV, showing CV2CoV induces higher neutralizing antibody titers and cross-neutralization against variants in rats.

bioRxiv · May 13, 2021 · PreprintImmunology

CVnCoV protects human ACE2 transgenic mice from ancestral B BavPat1 and emerging B.1.351 SARS-CoV-2

D. Hoffmann, B. Corleis, S. Rauch, N. Roth, J. Muehe, N. J. Halwe, L. Ulrich, C. Fricke, J. Schoen, A. Kraft, A. Breithaupt, K. Wernike, A. Michelitsch, F. Sick, C. Wylezich, , M. Beer

This study evaluates the efficacy of the CVnCoV mRNA vaccine against ancestral and emerging SARS-CoV-2 variants in a human ACE2 transgenic mouse model, showing complete protection against B.1.351.

bioRxiv · Mar 22, 2021Microbiology

Multi-species ELISA for the detection of antibodies against SARS-CoV-2 in animals

K. Wernike, A. Aebischer, A. Michelitsch, D. Hoffmann, C. Freuling, A. Balkema-Buschmann, A. Graaf, T. Mueller, N. Osterrieder, M. Rissmann, D. Rubbenstroth, J. Schoen, C. Schulz, J. Trimpert, L. Ulrich, , M. Beer

The paper develops a multi-species ELISA to detect SARS-CoV-2 antibodies in animals, achieving 100% specificity and 98.31% sensitivity across multiple species.

bioRxiv · Aug 26, 2020Microbiology

Dietary intervention improves health metrics and life expectancy of the genetically obese DU6 (Titan) mouse

A. Mueller-Eigner, A. Sanz-Moreno, I. de-Diego, A. Venkateswaran Venkatasubramani, M. Langhammer, R. Gerlini, B. Rathkolb, A. Aguilar-Pimentel, T. Klein-Rodewald, J. Calzada-Wack, L. Becker, S. Palma-Vera, B. Gille, I. Forne, A. Imhof, , S. Peleg

The study characterizes the Titan mouse as a model for metabolically unhealthy obesity and shows that dietary intervention improves its health and extends lifespan.

bioRxiv · May 11, 2020Physiology