Author

J. Winchester

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. M. Maga· 1 shared A. Porto· 1 shared A. S. Fox· 1 shared A. Summer· 1 shared B. E. Deverman· 1 shared C. M. Arokiaraj· 1 shared D. Boyer· 1 shared G. Deb· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperEvolutionary Biology

A. M. Maga

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Author profile →

3 papers

Recent·Most cited

Intravenous gene transfer throughout the brain of infant Old World primates using AAV

M. R. Chuapoco, N. Flytzanis, N. Goeden, J. C. Octeau, K. M. Roxas, K. Y. Chan, J. Scherrer, J. Winchester, R. J. Blackburn, L. J. Campos, C. M. Arokiaraj, T. F. Miles, M. J. Jang, J. Vendemiatti, B. E. Deverman, , V. Gradinaru

This paper introduces AAV.CAP-Mac, an engineered AAV variant that enables efficient systemic brain-wide gene delivery in infant Old World primates.

bioRxiv · Jan 8, 2022Bioengineering

SlicerMorph: An open and extensible platform to retrieve, visualize and analyze 3D morphology

S. Rolfe, S. Pieper, A. Porto, K. Diamond, J. Winchester, S. Shan, H. Kirveslahti, D. Boyer, A. Summer, A. M. Maga

SlicerMorph provides an open platform for retrieving, visualizing, and analyzing 3D morphology data to address challenges in quantitative organismal biology research.

bioRxiv · Nov 9, 2020Evolutionary Biology

Lgr5-mediated restraint of β-catenin is essential for B-lymphopoiesis and leukemia-initiation

K. N. Cosgun, M. E. Robinson, G. Deb, X. Yang, G. Xiao, T. Sadras, J. Lee, L. N. Chan, K. Kume, J. Winchester, Z. Chen, L. Yang, M. Mueschen

This study identifies Lgr5's role in restraining β-catenin to support B-lymphopoiesis and shows its therapeutic potential in B-ALL by targeting β-catenin hyperactivation.

bioRxiv · Mar 12, 2020 · PreprintCancer Biology