Author

J.-a. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Tewnion· 1 shared B. Anderson· 1 shared B. Guillory· 1 shared H. Chang· 1 shared H. Liu· 1 shared H. Zeng· 1 shared I. Lai· 1 shared I. Lee· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Tewnion

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2 papers

Recent·Most cited

Inducible lncRNA transgenic mice reveal continual role of HOTAIR in promoting breast cancer metastasis

Q. Ma, L. Yang, K. Tolentino, Y. Zhao, U. M. Lizenburger, Q. Shi, L. Zhu, M.-C. Tsai, J.-A. Chen, I. Lai, H. Zeng, L. Li, H. Chang

This study uses a transgenic mouse model to show that sustained HOTAIR expression promotes breast cancer metastasis and that its removal reverses metastatic traits, indicating an erasable epigenetic memory.

bioRxiv · Apr 21, 2022Cancer Biology

GHSR-1a is not Required for Ghrelin's Anti-inflammatory and Fat-sparing Effects in Cancer Cachexia

H. Liu, J. Luo, B. Guillory, J.-a. Chen, P. Zang, J. K. Yoeli, Y. Hernandez, I. Lee, B. Anderson, M. J. Storie, A. Tewnion, J. Garcia

This study shows ghrelin prevents white adipose tissue inflammation and atrophy in cancer cachexia, but GHSR-1a is only needed for its appetite-stimulating effect.

bioRxiv · Dec 6, 2019 · PreprintCancer Biology