ZBTB48 is a pioneer factor regulating B-cell-specific CIITA expression
G. Rane, V. L. S. Kuan, S. Wang, M. M. H. Mok, V. Khanchandani, J. Hansen, I. Norvaisaite, W. K. Yong, A. Jahn, V. Mukundan, Y. Shi, M. Osato, F. Li, D. Kappei
This study identifies ZBTB48 as a transcription factor that regulates B-cell-specific CIITA expression by binding to its promoter and establishing open chromatin.
bioRxiv · Jul 25, 2023Immunology