Author

K. J. Lavine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. Kreisel· 3 shared A. Kovacs· 2 shared A. L. Bredemeyer· 2 shared C. J. Weinheimer· 2 shared L. Lai· 2 shared O. Dmytrenko· 2 shared S. Guo· 2 shared V. Penna· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersImmunology

D. Kreisel

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 4, 2022

Hypoxia Sensing in Resident Cardiac Macrophages Regulates Monocyte Fate Specification following Ischemic Heart Injury

F. F. Kadyrov, A. L. Koenig, J. M. Amrute…·K. J. Lavine

This study shows that hypoxia sensing in cardiac macrophages influences monocyte differentiation into inflammatory states after heart injury.

DOI 10.1101/2022.08.04.502542

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivJan 28, 2021

Resident Cardiac Macrophages Mediate Adaptive Myocardial Remodeling

N. R. Wong, J. Mohan, B. Kopecky…·K. J. Lavine

This study identifies CCR2- resident cardiac macrophages as critical for adaptive myocardial remodeling in heart failure, showing their role in ventricular remodeling and coronary angiogenesis.

DOI 10.1016/j.immuni.2021.07.003

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivNov 4, 2020

SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis

A. L. Bailey, O. Dmytrenko, L. Greenberg…·K. J. Lavine

This study shows SARS-CoV-2 infects human engineered heart tissues, causing myocarditis-like features, and identifies ACE2 and proteases as entry factors.

DOI 10.1016/j.jacbts.2021.01.002

humanorganoid / primary culture

𝕏 PostBluesky

Cell BiologybioRxivMar 4, 2020

Chemokine receptor 2-targeted molecular imaging in pulmonary fibrosis

S. L. Brody, S. P. Gunsten, H. P. Luehmann…·Y. Liu

PET imaging of CCR2+ cells in lung fibrosis identifies therapeutic response in mouse models and shows perifibrotic signal in IPF patients.

DOI 10.1164/rccm.202004-1132oc

𝕏 PostBluesky