Author

K. L. Scott

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

C. T. Halfmann· 2 shared K. J. Roux· 2 shared T. P. Lele· 2 shared A. D. Hoefakker· 1 shared A. Jalali· 1 shared A. Katiyar· 1 shared A. M. Lentzsch· 1 shared A. T. Szafran· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCell Biology

C. T. Halfmann

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Nucleocytoplasmic transport rates are regulated by cellular processes that modulate GTP availability

K. L. Scott, C. T. Halfmann, A. D. Hoefakker, P. Purkayastha, T. C. Wang, T. P. Lele, K. Roux

The paper shows that changes in GTP availability, caused by cellular processes like migration, affect nucleocytoplasmic transport rates, impacting RNA export and protein synthesis.

bioRxiv · Dec 29, 2023Cell Biology

Mechanisms by which barrier-to-autointegration factor regulates dynamics of nucleocytoplasmic leakage and membrane repair following nuclear envelope rupture

C. T. Halfmann, K. L. Scott, R. M. Sears, K. J. Roux

This study identifies BAF's role in reducing nucleocytoplasmic leakage and facilitating membrane repair after nuclear envelope rupture through phosphoregulation of DNA binding.

bioRxiv · Dec 21, 2023 · PreprintCell Biology

The nucleus bypasses obstacles by deforming like a drop with surface tension mediated by lamin A/C

A. Katiyar, J. Zhang, J. D. Antani, Y. Yu, K. L. Scott, P. P. Lele, C. A. Reinhart-King, N. J. Sniadecki, K. J. Roux, R. B. Dickinson, T. P. Lele

The paper shows lamin A/C enables nuclear deformation through fibrous environments by acting like surface tension, allowing nuclei to bypass obstacles without rupturing.

bioRxiv · Mar 10, 2022 · PreprintCell Biology

Bacteria-to-human protein networks reveal origins of endogenous DNA damage

J. Xia, L.-Y. Chiu, R. B. Nehring, M. A. Bravo Nunez, Q. Mei, M. Perez, Y. Zhai, D. M. Fitzgerald, J. P. Pribis, Y. Wang, C. W. Hu, R. T. Powell, S. A. LaBonte, A. Jalali, M. L. Matadamas Guzman, , S. M. Rosenberg

The paper identifies DNA-damaging proteins in E. coli and their human homologs, showing they promote endogenous DNA damage and are overrepresented in cancer drivers.

bioRxiv · Jun 26, 2018Cancer Biology

Daam2 Driven Degradation Of VHL Promotes Gliomagenesis

W. Zhu, S. Krishna, C. Garcia, C.-C. J. Lin, K. L. Scott, C. Mohila, C. Creighton, S.-H. Yoo, H. K. Lee, B. Deneen

The paper identifies Daam2 as a factor promoting glioma formation by suppressing VHL expression through ubiquitination and degradation.

bioRxiv · May 19, 2017Cancer Biology