Biosynthesis- and Metabolomics-guided discovery of antimicrobial cyclopeptides against drug-resistant clinical isolates
Z. Cheng, B.-B. He, K. Lei, Y. Gao, Y. Shi, Z. Zhong, H. Liu, R. Liu, H. Zhang, S. Wu, W. Zhang, X. Tang, Y.-X. Li
This study discovers new Avi(Me)Cys-containing cyclopeptide antibiotics effective against drug-resistant bacteria using genome mining and metabolomics.
bioRxiv · Oct 26, 2023 · PreprintBiochemistry