K. Qin

Super-resolution optical imaging reveals accumulation of small mitochondria in the nucleoli of mouse embryos and stem cells

The paper uses super-resolution imaging to show mitochondrial DNA and mitochondria accumulate in nucleoli of mouse embryos and stem cells.

The molecular mechanism and evolutionary divergence of caspase 3/7-regulated gasdermin E activation

This study identifies the molecular mechanism and evolutionary divergence of caspase 3/7-regulated gasdermin E activation by analyzing cleavage specificity across species.

Transient EZH2 suppression by Tazemetostat during in vitro expansion maintains T cell stemness and improves adoptive T cell therapy

The paper shows that transient EZH2 inhibition with Tazemetostat during T cell expansion maintains stemness and improves adoptive T cell therapy outcomes in a murine model.

Identification of Six Thiolases and their Effects on Fatty Acid and Ergosterol Biosynthesis in Aspergillus oryzae

This study identifies six thiolases in Aspergillus oryzae and shows their roles in fatty acid and ergosterol biosynthesis, with some exhibiting dual functionality.

The differentiation of pluripotent stem cells towards transplantable endothelial progenitor cells

This study optimizes a protocol to differentiate pluripotent stem cells into endothelial progenitor cells with characteristics similar to healthy donor EPCs, showing differences in gene expression compared to PAH-derived EPCs.

Unveiling cells' local environment during cryopreservation by correlative in situ spatial and thermal analyses

This study uses correlative spatial and thermal analyses to reveal how cells interact with ice and vitreous fronts during cryopreservation, informing better cryoprotective media design.