Cell BiologybioRxiv
Protective effect of estrogen against intervertebral disc degeneration is attenuated by miR-221 through targeting estrogen receptor
B. Sheng, Y. Yuan, X. Liu…·L. Chang
This study shows estrogen protects against intervertebral disc degeneration by upregulating ER, but miR-221 reduces this protection by targeting ER.
DOI 10.1093/abbs/gmy017