Author

L. Dingle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 1 Cancer Biology· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Research Focus:spatial domain detection· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

J. A. Herrera· 2 shared R. V. Venkateswaran· 2 shared A. Hoyle· 1 shared A. P. Gilmore· 1 shared A. PICKARD· 1 shared A. Reid· 1 shared A. S. Bowman· 1 shared C. Lawless· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPathology

J. A. Herrera

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Learning performance and GABAergic pathway link to deformed wing virus in the mushroom bodies of naturally infected honey bees

S. Szymanski, D. Baracchi, A. S. Bowman, L. Dingle, F. Manfredini

This study finds that naturally infected honey bees with higher DWV loads show improved reversal learning, linked to increased GABAergic gene expression in mushroom bodies.

bioRxiv · Oct 8, 2023Animal Behavior & Cognition

Novel Laser Capture Microdissection-Proteomic Analysis Identifies Spatially Distinct Extracellular Matrix Signatures in the Core and Infiltrating Edge of Human Glioblastoma.

R. Pedley, D. T. Prescott, E. Appleton, L. Dingle, J. Minshull, P. I. D'Urso, I. Djoukhadar, A. P. Gilmore, F. Roncaroli, J. Swift

This paper develops an LCM-proteomics protocol to analyze spatial ECM differences in human glioblastoma, identifying distinct matrisome components between tumor epicenter and brain/tumor interface.

bioRxiv · Sep 1, 2022 · PreprintCancer Biology

The IPF fibroblastic focus is an active collagen biosynthesis factory embedded in a distinct extracellular matrix

J. A. Herrera, L. Dingle, M. A. Montero, R. Shah, R. V. Venkateswaran, J. F. Blaikley, C. Lawless, M. A. Schwartz

The paper uses spatial proteomics to show that the IPF fibroblastic focus is a major site of collagen biosynthesis with distinct ECM composition compared to surrounding tissues.

bioRxiv · Nov 6, 2021Pathology

Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis

J. CHANG, A. PICKARD, J. A. Herrera, S. O'Keefe, M. Hartshorn, R. GARVA, A. Hoyle, L. Dingle, C. Zeltz, J. Wong, A. Reid, R. V. Venkateswaran, Y. Lu, P. Caswell, S. High, , K. E. KADLER

This study shows that circadian-regulated endocytic recycling is essential for collagen fibril assembly and is disrupted in fibrosis.

bioRxiv · Mar 25, 2021Cell Biology