Author

L. Lou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

C. M. Linardic· 1 shared C. Xu· 1 shared D. G. Kirsch· 1 shared D. Kuang· 1 shared D. M. Cardona· 1 shared D. Zhan· 1 shared F. Cheng· 1 shared G. Wang· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

C. M. Linardic

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2 papers

Recent·Most cited

Proteomic Stratification of Prognosis and Treatment Options for Small Cell Lung Cancer

Z. Huo, Y. Duan, D. Zhan, X. Xu, N. Zheng, J. Cai, R. Sun, J. Wang, F. Cheng, Z. Gao, C. Xu, W. Liu, Y. Dong, S. Ma, Q. Zhang, , Y. Wang

This study uses proteomic profiling to stratify small cell lung cancer into three subtypes with distinct clinical outcomes and treatment responses, identifying potential therapeutic targets and improving prognosis prediction.

bioRxiv · Oct 22, 2023 · PreprintCancer Biology

Expression of the CIC-DUX4 fusion oncoprotein mimics human CIC-rearranged sarcoma in genetically engineered mouse models

P. G. Hendrickson, K. M. Oristian, M. R. Browne, L. Lou, Y. Ma, D. M. Cardona, C. M. Linardic, D. G. Kirsch

This study generates genetically engineered mouse models of CIC-DUX4 sarcoma that spontaneously develop tumors and express the fusion protein, validating CIC-DUX4 as a transcriptional activator.

bioRxiv · Sep 26, 2023 · PreprintCancer Biology