Haptenic adducts of beta-lactam antibiotics elicit antibody responses with narrow clonality and specificity
L. P. Deimel, L. Moynie, G. Sun…·Q. J. Sattentau
This study investigates how penicillin G forms immunogenic adducts on proteins and elicits specific antibody responses in mice, revealing clonal dominance and limited cross-reactivity with other beta-lactam antibiotics.