Cell BiologyeLifePeer-reviewed
Trabid patient mutations impede the axonal trafficking of adenomatous polyposis coli to disrupt neurite growth
D. Frank, M. Bergamasco, M. Mlodzianoski…·H. Tran
This study identifies Trabid mutations that disrupt APC trafficking and neurite growth by impairing DUB activity or STRIPAK binding, leading to neurodevelopmental defects.
DOI 10.7554/elife.90796