Author

M. Emani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Greka· 2 shared A. Weins· 2 shared C. Kim· 2 shared A. Anandkumar· 1 shared A. Brace· 1 shared A. Campbell· 1 shared A. Clark· 1 shared A. R. Clyde· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

A. Greka

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Intelligent Resolution: Integrating Cryo-EM with AI-driven Multi-resolution Simulations to Observe the SARS-CoV-2 Replication-Transcription Machinery in Action

A. Trifan, D. Gorgun, Z. Li, A. Brace, M. Zvyagin, H. Ma, A. R. Clyde, D. A. Clark, M. Salim, D. Hardy, T. Burnley, L. Huang, J. McCalpin, M. Emani, H. Yoo, , A. Ramanathan

This study develops an AI-driven multi-resolution simulation workflow to study SARS-CoV-2 RTC dynamics, combining cryo-EM with mesoscale simulations and AI methods.

bioRxiv · Oct 9, 2021 · PreprintBiophysics

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

M. Malimova, E.-H. Sidhom, A. Satyam, M. Dvela-Levitt, M. Melanson, B. T. Chamberlain, S. L. Alper, J. Santos, J. Gutierrez, A. Subramanian, E. Grinkevich, E. R. Bricio, C. Kim, A. Clark, A. Watts, , A. Greka

The paper identifies Fostamatinib as a potential repurposing drug for acute lung injury by reducing MUC1 protein levels in preclinical models.

Cell Reports Medicine · Nov 1, 2020Peer-reviewedCell Biology

Blocking the Rac1-TRPC5 pathway protects human podocytes

Y. Zhou, C. Kim, J. L. B. Pablo, F. Zhang, J. Y. Jung, L. Xiao, S. Bazua, M. Emani, C. Hopkins, A. Weins, A. Greka

This study shows TRPC5 inhibition protects human podocytes from injury in vitro and in vivo, supporting its therapeutic potential for kidney diseases.

bioRxiv · Aug 28, 2020 · PreprintCell Biology