A. Unnikrishnan

Environmental Factors Associated with Incidence and Distribution of V. parahaemolyticus and V. vulnificus in Chesapeake Bay, Maryland, USA: A three-year case study

This study identifies environmental factors influencing Vibrio parahaemolyticus and Vibrio vulnificus incidence in Chesapeake Bay, finding that water temperature ≥20°C and salinity 9-20 PPT increase risk, with water samples being more reliable indicators.

Dysregulated expression of Hoxa1 isoforms in hematopoietic stem and progenitor cells causes myelodysplastic syndromes.

This study shows that dysregulated Hoxa1 isoforms in hematopoietic stem and progenitor cells cause myelodysplastic syndromes and provide mouse models for disease progression.

Single cell genotyping of matched bone marrow and peripheral blood cells in treatment naive and AZA-treated MDS and CMML

This study examines the contribution of mutated hematopoietic stem and progenitor cells to blood cell populations in MDS and CMML before and after AZA treatment.

Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α

This study shows 17α-estradiol improves metabolic parameters and slows aging in male mice and rats through estrogen receptor α, primarily acting in the liver and hypothalamus.

DNA Binding Induces a cis to trans Switch in Cre Recombinase to Enable Intasome Assembly

This paper uses NMR to show that Cre recombinase undergoes a cis-to-trans conformational switch upon DNA binding, enabling intasome assembly and DNA recombination.

RNA splicing alterations induce a cellular stress response associated with poor prognosis in AML

The paper identifies RNA splicing alterations in AML patients without splicing factor mutations, linking them to stress response and poor prognosis through machine learning.

Biodiversity clock and conservation triangle: Integrative platform for biodiversity monitoring, evaluation, and preemptive conservation intervention

The paper introduces biodiversity clock and conservation triangle as tools for integrating biodiversity monitoring and conservation strategies to enable preemptive interventions.