Author

M. Hewison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Approach:biophysical modeling· 1

Frequent Co-Authors

C. Jenkinson· 2 shared A. Manousopoulou· 1 shared A. Philp· 1 shared A. Smith· 1 shared B. Ashley· 1 shared C. Cooper· 1 shared C. Flaxman· 1 shared C. H. White· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPhysiology

C. Jenkinson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Placental uptake and metabolism of 25(OH)Vitamin D determines its activity within the fetoplacental unit

B. Ashley, C. Simner, A. Manousopoulou, C. Jenkinson, F. Hey, J. M. Frost, F. I. Rezwan, C. H. White, E. M. Lofthouse, E. Hyde, L. Cooke, S. Barton, P. Mahon, E. M. Curtis, R. J. Moon, , J. K. Cleal

This study shows the human placenta actively transports and metabolizes 25(OH)D3 into active vitamin D metabolites, influencing fetal development through placental transcriptome and proteome changes.

eLife · Mar 8, 2022Peer-reviewedPhysiology

Vitamin D modulation of mitochondrial oxidative metabolism and mTOR enforces stress tolerance and anti-cancer responses

M. Quigley, S. Rieger, E. Capobianco, Z. Wang, H. Zhao, M. Hewison, T. S. Lisse

This study shows vitamin D reduces mitochondrial ROS and oxidative phosphorylation while enhancing stress tolerance and anti-cancer responses in osteosarcoma cells.

bioRxiv · Jun 8, 2021Cancer Biology

Association between vitamin D deficiency and exercise capacity in patients with CKD, a cross-sectional analysis

E. L. Watson, T. Wilkinson, T. O'Sullivan, L. Baker, D. Gould, S. Xenophontos, M. Graham-Brown, R. Major, C. Jenkinson, M. Hewison, A. Philp, A. Smith

This study examines the relationship between vitamin D deficiency and exercise capacity in CKD patients, finding no strong link to muscle size but a possible role in reduced exercise capacity.

bioRxiv · Oct 26, 2020Cell Biology

Vitamin D-binding protein is required for the maintenance of α-cell function and glucagon secretion

K. Viloria, D. Nasteska, L. J. B. Briant, S. Helsing, D. Larner, N. H. F. Fine, F. B. Ashford, G. da Silva Xavier, M. Jimenez Ramos, J. E. Manning Fox, P. E. MacDonald, I. Akerman, G. G. Lavery, C. Flaxman, N. G. Morgan, , D. J. Hodson

This study shows that vitamin D-binding protein (DBP) is essential for maintaining β-cell function and glucagon secretion, with reduced DBP expression observed in late-onset type 1 diabetes.

bioRxiv · Dec 19, 2019 · PreprintPhysiology