Author

M. Jovanovic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. C. Johns· 1 shared A. E. McDermott· 1 shared A. E. van Vlimmeren· 1 shared A. M. Ali· 1 shared A. M. S. Grilo· 1 shared A. Sawas· 1 shared A. Tripathi· 1 shared C. A. Chartier· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. C. Johns

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Allosteric regulation of the tyrosine phosphatase PTP1B by a protein-protein interaction

C. A. Chartier, V. A. Woods, Y. Xu, A. E. van Vlimmeren, A. C. Johns, M. Jovanovic, A. E. McDermott, D. A. Keedy, N. H. Shah

This paper shows that Grb2 binding to PTP1B allosterically enhances its catalytic activity through structural changes, revealing a new regulatory mechanism for PTP1B in cell signaling.

bioRxiv · Jul 16, 2024Biochemistry

Poly-basic peptides and polymers as new drug candidate against Plasmodium falciparum

R. Sivakumar, K. Floyd, E. Jessey, J. Kim Kim, P. Bayguinov, J. A. J. Fitzpatrick, D. Goldfarb, M. Jovanovic, A. Tripathi, S. Djuranovic, S. Pavlovic Djuranovic

This study shows poly-lysine peptides and their modifications can reduce Plasmodium falciparum in human erythrocytes in vitro, with potential as new antimalarial drugs.

bioRxiv · Sep 16, 2023 · PreprintMicrobiology

CK1 Delta Is an mRNA Cap-Associated Protein That Drives Translation Initiation and Tumor Growth

I. Pal, A. M. S. Grilo, L. E. Berchowitz, S. DasSharma, P. S. Mundi, A. M. Ali, M. L. Martin, M. Safari, L. Scotto, E. Malkovskiy, A. Sawas, S. Mukherjee, O. A. O'Connor, M. Jovanovic, C. Deng

This paper identifies CK1 delta as an mRNA cap-associated protein that drives translation initiation and tumor growth in blood cancers, with distinct roles in solid tumors.

bioRxiv · Feb 20, 2020 · PreprintCancer Biology

Structural basis of transcription inhibition by the DNA mimic protein Ocr of bacteriophage T7

X. Zhang, F. Ye, I. Kotta-Loizou, M. Jovanovic, X. Liu, D. T. F. Dryden, M. Buck

This study reveals that the Ocr protein from bacteriophage T7 inhibits host transcription by binding to RNA polymerase and competing with sigma factors, providing a structural basis for its dual role in evading host defenses.

eLife · Feb 10, 2020Peer-reviewedBiophysics

Ribosome dimerization prevents loss of essential ribosomal proteins during quiescence

H. Feaga, M. Kopylov, J. K. Kim, M. Jovanovic, J. Dworkin

This study shows that HPF in Bacillus subtilis prevents loss of essential ribosomal proteins during quiescence by mediating ribosome dimerization.

bioRxiv · Oct 16, 2019 · PreprintMicrobiology