M. Kudryashev

Streamlined Structure Determination by Cryo-Electron Tomography and Subtomogram Averaging using TomoBEAR

TomoBEAR streamlines cryo-electron tomography and subtomogram averaging for high-resolution macromolecular structure determination with minimal human intervention.

Elucidating the activation mechanism for GBP1 oligomerization

This study reveals the activation mechanism of GBP1 oligomerization through cryo-EM structures, showing nucleotide-dependent conformational changes drive dimerization, oligomerization, and membrane binding for pathogen encapsulation.

Determining The Structure of the Bacterial Voltage-gated Sodium Channel NaChBac Embedded in Liposomes by Cryo Electron Tomography and Subtomogram Averaging

This paper determines the structure of the bacterial voltage-gated sodium channel NaChBac in liposomes using cryo electron tomography and subtomogram averaging, showing it is 10% wider than its nanodisc structure.

KAHRP dynamically relocalizes to remodeled actin junctions and associates with knob spirals in P. falciparum-infected erythrocytes

This study uses super-resolution microscopy to show KAHRP relocalizes to remnant actin junctions and associates with spiral scaffolds in P. falciparum-infected erythrocytes.

Subnanometer-resolution structure determination in situ by a hybrid subtomogram averaging - single particle cryoEM - workflow

The paper introduces a hybrid workflow combining subtomogram averaging and single-particle cryoEM to improve resolution in structural determination, achieving subnanometer resolution for tobacco mosaic virus and RyR1 ion channel.