M. M. Hassan

This study presents high-resolution atomic structures of two Giardiavirus strains, revealing structural features associated with extracellular transmission and virulence in Giardia duodenalis.

This study evaluates how electrophilic modifications to JQ1 affect DCAF16 trans-labeling and BRD4 degradation, showing a correlation between warhead exposure and degradation efficiency.

This study identifies 2-HPA as a novel mPR antagonist from marine algae Padina arborescens, showing specific inhibitory activity in vitro and in vivo.

The study shows the PAN domain in G-type lectin receptor-like kinases suppresses JA/ET defense pathways in plants by promoting receptor degradation.

This paper describes a new mechanism for molecular glue degraders called template-assisted covalent modification, showing how BRD4 degraders recruit CUL4DCAF16 to degrade BRD4.

This paper introduces a split selectable marker system using inteins for Agrobacterium-mediated co-transformation in plants, enabling the simultaneous insertion of multiple genes into Arabidopsis and poplar.

This study investigates the phytochemical composition and antibacterial potential of Onychium japonicum, finding it rich in bioactive compounds and active against multidrug-resistant bacteria.

This study develops plant-based biosensors to detect CRISPR/Cas tools in real-time, demonstrating their effectiveness in detecting various CRISPR functions in multiple plant species.

This paper develops a split-nCas9 system using intein-mediated reassembly for efficient base editing in plants.

This paper identifies a hamster model, Phodopus roborovskii SH101, that exhibits systemic SARS-CoV-2 infection with clinical symptoms similar to human COVID-19.

This study uses an ex-vivo lung biofilm model to assess antibiotic tolerance and virulence of Pseudomonas aeruginosa, showing minimal bacterial load reduction and increased virulence factors with certain antibiotics.

This study develops an ex vivo pig lung model of cystic fibrosis to study Staphylococcus aureus infection, showing clinically relevant features like small colony variants and antibiotic tolerance.