G. Yuan

This paper develops an engineered filamentous phage that delivers CRISPR-AsCas12f1 to target Ralstonia solanacearum's virulence gene hrpB, effectively controlling bacterial wilt in tobacco.

The paper designs mutated pRN1 plasmid backbones to evade CRISPR immunity in Saccharolobus islandicus, enabling stable plasmid vectors and a dual plasmid system for genetic studies.

This study shows that sustained store-operated calcium entry (SOCE) and chromatin accessibility in iTregs lead to phenotypical instability, unlike tTregs.

This study functionally characterizes candidate sex determination genes in Salix purpurea using Arabidopsis, supporting ARR17 and GATA15 as master regulators and identifying downstream transcription factors.

This paper introduces a split selectable marker system using inteins for Agrobacterium-mediated co-transformation in plants, enabling the simultaneous insertion of multiple genes into Arabidopsis and poplar.

The paper analyzes sex differential genes across seven tissues in BXD mouse strains, revealing organ- and chromosome-dependent expression patterns and functional roles.

This study shows that synthetic sensor NLR receptors require multiple interfaces within and outside their integrated domain to recognize noncorresponding effectors and activate resistance.

This study shows that HIF-1α and HIF-2α antagonism in the carotid body and adrenal medulla regulates redox balance and hypoxia responses, maintaining blood pressure and respiration.

This study develops plant-based biosensors to detect CRISPR/Cas tools in real-time, demonstrating their effectiveness in detecting various CRISPR functions in multiple plant species.

This paper develops a split-nCas9 system using intein-mediated reassembly for efficient base editing in plants.

This study identifies mitochondrial biomarkers and pathways in sepsis using bioinformatics analysis of gene expression data from a public dataset.

This study identifies biomarkers and candidate regulators in multiple myeloma under AURKA knockout using bioinformatics analysis of gene expression data.

This study compares the secretome of Magnaporthe oryzae wild type and Δalg3 mutants, identifying 51 proteins requiring ALG3 for secretion and showing their roles in virulence and cell wall integrity.

This study shows HIV-associated extracellular vesicles enhance KSHV infectivity in oral epithelial cells via TAR RNA and EGFR, suggesting EGFR inhibition as a potential therapeutic strategy.

This study identifies CDX2-regulated genes and regulatory elements in mouse embryos, revealing how CDX2 represses pluripotent genes during trophectoderm and inner cell mass specification.