Author

M. Vien

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Approach:simulation· 1

Frequent Co-Authors

B. Onoa· 2 shared C. Canari-Chumpitaz· 2 shared C. D. Diaz-Celis· 2 shared M. Zhang· 2 shared A. Accardi· 1 shared A. Chen· 1 shared C. A. Ahern· 1 shared C. Bustamante· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersBiophysics

B. Onoa

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Assignment of structural transitions during mechanical unwrapping of nucleosomes and their disassembly products

C. D. Diaz-Celis, C. Canari-Chumpitaz, R. P. Sosa, J. P. Castillo, M. Zhang, E. Cheng, A. Chen, M. Vien, J. Kim, B. Onoa, C. J. Bustamante

This study uses optical tweezers and FRET to identify DNA segments unwrapped during nucleosome mechanical transitions, revealing distinct low- and high-force unwrapping processes.

bioRxiv · Apr 13, 2022Biophysics

Molecular Organization of the Early Stages of Nucleosome Phase Separation Visualized by Cryo-Electron Tomography

M. Zhang, C. D. Diaz-Celis, B. Onoa, C. Canari-Chumpitaz, K. I. Requejo, J. Liu, M. Vien, E. Nogales, G. Ren, C. Bustamante

This study uses cryo-electron tomography and deep learning to visualize the molecular organization of nucleosome phase separation stages, revealing a two-step process and the role of histone H1 in condensate transformation.

bioRxiv · Sep 1, 2021Biophysics

Divergent Cl-and H + pathways underlie transport coupling and gating in CLC exchangers and channels

A. Accardi, L. Leisle, Y. Xu, E. Fortea, J. D. Galpin, M. Vien, C. A. Ahern, S. Berneche

This study identifies an aromatic pathway in CLC proteins that enables H+ transport and gating, revealing distinct and conserved routes for Cl- and H+ movement.

bioRxiv · Sep 5, 2019Biochemistry