Author

M. Wehbe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. T. Wilson· 2 shared A. K. von Lersner· 1 shared A. M. Pyle· 1 shared A. Richmond· 1 shared A. Weaver· 1 shared A. Zijlstra· 1 shared B. H. Sung· 1 shared B. Vergier· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBioengineering

J. T. Wilson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Nanoparticle RIG-I Agonist for Cancer Immunotherapy

L. Wang-Bishop, M. Wehbe, L. E. Pastora, J. Yang, K. M. Garland, K. W. Becker, C. S. Carson, K. N. Gibson-Corley, D. Ulkoski, V. Krishnamurthy, O. Fedorova, A. Richmond, A. M. Pyle, J. T. Wilson

This paper develops SLR-LNPs, a nanoparticle-based RIG-I agonist, showing enhanced tumor immunogenicity and improved response to immune checkpoint inhibitors in mouse cancer models.

bioRxiv · Apr 25, 2023 · PreprintBioengineering

Absence of the bile acid enzyme CYP8B1 increases brain chenodeoxycholic acid and reduces neuronal excitotoxicity in mice

V. F. Monteiro-Cardoso, X. Y. Yeo, H.-G. Bae, D. Castano Mayan, M. Wehbe, S. Lee, K. Krishna-K, S. H. Baek, L. F. Palomera, S. Shanmugam, K. P. Sem, M. P. Parsons, M. R. Hayden, E. A. Liehn, S. Sajikumar, , R. R. Singaraja

This study shows that absence of CYP8B1 increases brain chenodeoxycholic acid (CDCA) levels, reducing neuronal excitotoxicity and stroke infarct area in mice.

bioRxiv · Dec 11, 2022 · PreprintPhysiology

The E-cadherin-ESR1-GRPR axis defines a sex-specific metastatic pathway in melanoma

J. H. Raymond, M. Schonau, V. Petit, Z. Aktary, F. Luciani, M. Wehbe, I. Davidson, C.-L. Tomasetto, F. Mahuteau-Betzer, B. Vergier, L. Larue, V. Delmas

This study identifies an E-cadherin-ER-GRPR axis that drives sex-specific melanoma metastasis and shows GRPR inhibition reduces metastasis in vivo.

bioRxiv · Dec 2, 2022 · PreprintCancer Biology

EV Fingerprinting: Resolving extracellular vesicle heterogeneity using multi-parametric flow cytometry

A. K. von Lersner, F. C. L. Fernandes, P. M. M. Ozawa, T. Vagner, S. M. Lima, B. H. Sung, M. Wehbe, K. Franze, J. T. Wilson, J. M. Irish, A. Weaver, D. Di Vizio, A. Zijlstra

EV Fingerprinting uses flow cytometry to resolve EV heterogeneity and detect tumor-derived EVs in plasma.

bioRxiv · Nov 10, 2022 · PreprintCell Biology