Author

N. Burger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. Djurabekova· 1 shared A. Von Kriegsheim· 1 shared C. A. Powell· 1 shared C. Bennett· 1 shared C. Frezza· 1 shared C. Xu· 1 shared D. G. Ryan· 1 shared E. Nikitopoulou· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

A. Djurabekova

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural basis of respiratory complexes adaptation to cold temperatures

Y.-C. Shin, P. Latorre-Muro, A. Djurabekova, O. Zdorevskyi, C. Bennett, N. Burger, K. Song, C. Xu, V. Sharma, M. Liao, P. Puigserver

This study identifies a cold-induced conformation of respiratory complex CI:III2 using cryo-EM and simulations, revealing structural changes that enhance electron transfer efficiency in cold environments.

bioRxiv · Jan 16, 2024 · PreprintCell Biology

A comprehensive landscape of the zinc-regulated human proteome

N. Burger, M. Mittenbuhler, H. Xiao, S. Shin, L. Bozi, S. Wei, H.-G. Sprenger, Y. Sun, Y. Zhu, N. Darabedian, J. Petrocelli, P. Latorre Muro, J. Che, E. T. Chouchani

This study maps zinc-regulated cysteine sites in the human proteome, identifies cancer dependencies, and reveals a mechanism of zinc-induced cytotoxicity in lung cancers.

bioRxiv · Jan 4, 2024 · PreprintCell Biology

Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism

D. G. Ryan, M. Yang, H. A. Prag, G. R. Blanco, E. Nikitopoulou, M. Segarra-Mondejar, C. A. Powell, T. Young, N. Burger, J. L. Miljkovic, M. Minczuk, M. P. Murphy, A. Von Kriegsheim, C. Frezza

This study investigates the effects of TCA cycle inhibition on redox and amino acid metabolism, revealing ATF4-dependent metabolic rewiring and distinct responses between FH and SDH inhibition.

bioRxiv · Jul 27, 2021Biochemistry