Author

N. Catanzaro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

A. Brown· 2 shared F. Moreira· 2 shared G. De la Cruz· 2 shared M. Mallory· 2 shared R. S. Baric· 2 shared T. D. Scobey· 2 shared T. P. Sheahan· 2 shared A. J. Brown· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

A. Brown

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Vaccine-mediated protection against merbecovirus and sarbecovirus challenge in mice

D. Martinez, A. R. Schaefer, T. Gavitt, M. Mallory, E. Lee, N. Catanzaro, H. Chen, K. Gully, T. D. Scobey, P. Korategere, A. Brown, L. Smith, R. Parks, M. Barr, A. Newman, , K. O. Saunders

This study develops a trivalent RBD nanoparticle vaccine that protects mice against both merbecovirus and sarbecovirus challenges, including SARS-CoV, MERS-CoV, and SARS-CoV-2.

Cell Reports · Oct 1, 2023Peer-reviewedImmunology

Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential

D. R. Martinez, F. Moreira, M. R. Zweigart, K. L. Gully, G. De la Cruz, A. Brown, L. E. Adams, N. Catanzaro, B. Yount, T. J. Baric, M. Mallory, H. Conrad, S. R. May, S. Dong, T. D. Scobey, , T. P. Sheahan

This study evaluates the antiviral efficacy of GS-5245 against multiple SARS-CoV-2 variants and other coronaviruses, showing broad in vitro activity and protective effects in animal models.

bioRxiv · Jun 27, 2023 · PreprintMicrobiology

Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice

A. J. Brown, J. Won, R. Wolfisberg, U. Fanhoe, N. Catanzaro, A. West, F. Moreira, M. Nogeuira Batista, M. T. Ferris, C. Linnertz, S. R. Leist, C. Nguyen, G. De la Cruz, B. Midkiff, Y. Xia, , T. P. Sheahan

The paper infects diverse mouse strains with a hepacivirus and shows host genetic variation influences viral clearance, chronicity, and liver fibrosis outcomes.

bioRxiv · Mar 18, 2023Microbiology

Structurally conserved domains between flavivirus and alphavirus fusion glycoproteins contribute to replication in mammals and infectious virion production.

M. V. Rangel, N. Catanzaro, S. A. Thannickal, K. A. Crotty, M. G. Noval, K. E. E. Johnson, E. Ghedin, H. M. Lazear, K. A. Stapleford

This study identifies structurally conserved domains in flavivirus and alphavirus fusion glycoproteins that contribute to replication and infectious virion production, suggesting potential targets for broad-spectrum antivirals.

Journal of Virology · Jan 26, 2022Peer-reviewedMicrobiology