Author

N. Harmston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Moreno-Moral· 1 shared C. S. Wong· 1 shared D. A. Ang· 1 shared D. P. V. de Kleijn· 1 shared E. H. Z. Chua· 1 shared E. Petretto· 1 shared G. Krishnan Priyadarshini· 1 shared H. S. Chin· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

A. Moreno-Moral

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

FOXO-regulated Deaf1 controls muscle regeneration through autophagy

K. Y. Goh, W. X. Lee, S. M. Choy, G. Krishnan Priyadarshini, K. Chua, Q. H. Tan, S. Y. Low, H. S. Chin, C. S. Wong, S.-Y. Huang, N. Y. Fu, J. Nishiyama, N. Harmston, H.-W. Tang

This study identifies Deaf1 as a FOXO-regulated factor that controls muscle regeneration via autophagy, showing its critical role in muscle stem cell survival and regeneration.

bioRxiv · Jan 12, 2024Cell Biology

Aberrant non-canonical NF-kappaB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma

D. A. Ang, J.-M. Carter, K. Deka, J. H. L. TAN, J. Zhou, Q. Chen, W. J. Chng, N. Harmston, Y. Li

This study shows that aberrant non-canonical NF-kappaB signalling reprograms the epigenome to drive oncogenic transcriptomes in multiple myeloma by promoting super-enhancers and cis-regulatory interactions.

bioRxiv · Jan 9, 2024Cancer Biology

Wnt signaling rescues amyloid beta induced stem cell loss

P. Kaur, E. H. Z. Chua, W. K. Lim, N. Harmston, N. S. Tolwinski

The paper shows that Wnt signaling rescues amyloid beta-induced stem cell loss by reducing inflammation and modulating aging-related genes.

bioRxiv · Sep 6, 2021Cell Biology

In vivo generation of post-infarct mouse cardiac muscle by cardiomyocyte progenitors produced with a reproducible laminin-promoted human stem cell differentiation system

L. Yap, J.-W. Wang, A. Moreno-Moral, L. Y. Chong, Y. Sun, N. Harmston, X. Wang, S. Y. Chong, M. K. Ohman, H. Wei, R. Bunte, S. Ghosh, S. Cook, O. Hovatta, D. P. V. de Kleijn, , K. Tryggvason

This paper develops a reproducible method to generate cardiac muscle progenitors from human stem cells using laminin-221, which can form human heart muscle in vivo after transplantation.

bioRxiv · Nov 26, 2018 · PreprintCell Biology