MicrobiologybioRxiv
N6-methyladenosine modification of HIV-1 RNA evades RIG-I-mediated sensing to suppresses type-I interferon induction in monocytic cells
S. Chen, S. Kumar, N. Tirumuru…·L. Wu
This study shows that HIV-1 RNA's m6A modifications suppress type-I interferon induction in monocytic cells by evading RIG-I sensing.
DOI 10.1371/journal.ppat.1009421