Author

O. Weigert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

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Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2

Frequent Co-Authors

V. Passerini· 3 shared D. Fitzgerald· 2 shared F. Czernilofsky· 2 shared G. P. Nolan· 2 shared H. Voehringer· 2 shared M. A. Baertsch· 2 shared M. Knoll· 2 shared N. Liebers· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

V. Passerini

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Author profile →

4 papers

Recent·Most cited

Multimodal and spatially resolved profiling identifies distinct patterns of T-cell infiltration in nodal B-cell lymphoma entities

T. Roider, M. A. Baertsch, D. Fitzgerald, H. Voehringer, B. J. Brinkmann, F. Czernilofsky, M. Knoll, L. Llao-Cid, P.-M. Bruch, N. Liebers, C. M. Schuerch, V. Passerini, A. Brobeil, G. Mechtersheimer, C. Mueller-Tidow, , S. Dietrich

Nature Cell Biology · Mar 1, 2024Peer-reviewedCancer Biology

ARID1A Mutations Protect Follicular Lymphoma from FAS-dependent Immune Surveillance by Reducing RUNX3/ETS1-Driven FAS-Expression

M. Antoniolli, M. Solovey, C. D. Strobl, D. Bararia, W. D. Keay, J. A. Hildebrand, L. Adolph, M. Heide, V. Passerini, T. Freyholdt, L. Wange, W. Enard, S. Thieme, H. Blum, M. Rudelius, , O. Weigert

This study identifies ARID1A mutations in follicular lymphoma that reduce FAS expression, enabling immune evasion by disrupting RUNX3/ETS1 regulation.

bioRxiv · Dec 12, 2023 · PreprintCancer Biology

A single-cell multi-omic and spatial atlas of B cell lymphomas reveals differentiation drives intratumor heterogeneity

D. Fitzgerald, T. Roider, M. A. Baertsch, A. Kibler, A. Horlova, E. K. Chung, H. Voehringer, A. Mathioudaki, B. Budeus, V. Passerini, M. Knoll, J. Mammen, L. Li, L. Caille, F. Czernilofsky, , W. Huber

This study reveals that cellular differentiation drives intratumor heterogeneity in B-cell lymphomas, with distinct maturation states associated with different survival outcomes.

bioRxiv · Nov 6, 2023 · PreprintCancer Biology

Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma

P. Mondello, S. Tadros, M. Teater, L. Fontan, A. Chang, N. Jain, S. Singh, M. C. J. Ma, H. Yang, E. Toska, S. Alig, M. Durant, E. de Stanchina, A. Mottok, L. Nastoupil, , M. Green

This paper shows that HDAC3 inhibitors reverse CREBBP mutation-driven epigenetic changes in lymphoma, inhibiting tumor growth and restoring immune surveillance.

bioRxiv · Jan 27, 2019Cancer Biology