M. Green

The Outer Kinetochore Proteins KNL-1 and Ndc80 complex are Required to Pattern the Central Nervous System

This study shows that KNL-1 and the NDC-80 complex are essential for proper axonal organization in C. elegans, revealing a non-canonical role for the KMN network in nervous system development.

Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of oesophageal cancer

The paper investigates how CDKN2A and other 9p21 gene losses influence oesophageal cancer progression, finding context-dependent effects on survival and immune infiltration.

Near infrared conjugated polymer nanoparticles (CPN) for tracking cells using fluorescence and optoacoustic imaging

This study develops near-infrared conjugated polymer nanoparticles (CPNs) for cell tracking using fluorescence and optoacoustic imaging, showing they outperform indocyanine green (ICG) in some applications.

Resistance exercise protects mice from protein-induced fat accretion

This study shows that high protein diets in mice can enhance muscle growth from resistance exercise without increasing fat mass, but do not improve glycemic control.

Microenvironmental Ammonia Enhances T cell Exhaustion in Colorectal Cancer

This study shows that ammonia accumulation in the colorectal cancer microenvironment promotes T cell exhaustion and treatment resistance, and that reducing ammonia improves immunotherapy efficacy.

Targeted cancer therapy induces APOBEC fuelling the evolution of drug resistance

This study shows that targeted cancer therapy induces APOBEC-mediated mutagenesis, promoting drug resistance by increasing genetic diversity through mechanisms involving NF-κB activation and reduced DNA repair.

The life-history fitness of F1 hybrids of the microcrustacean Daphnia pulex and D. pulicaria (Crustacea, Anomopoda)

This study examines life-history fitness in F1 hybrids of Daphnia pulex and D. pulicaria, finding heterosis in four out of five traits, suggesting no major genetic incompatibilities and early speciation stage.

Structure of the Glutamate-Like Receptor GLR3.2 ligand-binding domain

The paper determines the crystal structures of Arabidopsis thaliana GLR3.2 ligand-binding domain in complex with glycine and methionine, revealing structural similarities to iGluRs and explaining ligand promiscuity.

Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma

This paper shows that HDAC3 inhibitors reverse CREBBP mutation-driven epigenetic changes in lymphoma, inhibiting tumor growth and restoring immune surveillance.

Risk Factors for Fouling Biomass: Evidence from Small Vessels in Australia

The paper quantifies factors influencing biofouling biomass on small vessels using multilevel modeling, finding that cleaning frequency, usage, and antifouling paint type significantly affect wet biomass.