Author

P. Aviles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. Cuevas· 2 shared A. Garcia-Sastre· 1 shared A. Losada· 1 shared A. Zachayus· 1 shared A.-K. Reuschl· 1 shared B. Clotet· 1 shared c. capelli· 1 shared C. Elly· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

C. Cuevas

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Novel synthetic ecteinascidins exhibit potent anti-melanoma activity by suppressing super-enhancer-driven oncogenic transcription

M. Cigrang, j. Obid, i. Davidson, M. Nogaret, t. ye, g. davidson, P. Catez, P. Berico, c. capelli, C. Marechal, A. Zachayus, C. Elly, T.-K. Li, E. Compe, P. Aviles, , F. Coin

This study shows novel synthetic ecteinascidins effectively treat melanoma by inhibiting super-enhancer-driven oncogenic transcription, even in resistant models.

bioRxiv · Mar 26, 2024 · PreprintCancer Biology

Unraveling the antiviral activity of plitidepsin by subcellular and morphological analysis

M. Sachse, R. Tenorio, I. Fernandez de Castro, J. Munoz-Basagoiti, D. Perez-Zsolt, D. Raich-Regue, J. Rodo, A. Losada, P. Aviles, C. Cuevas, R. Paredes, J. Segales, B. Clotet, J. Vergara-Alert, N. Izquierdo-Useros, C. Risco

This study uses electron microscopy to show plitidepsin blocks SARS-CoV-2 replication organelles and virus morphogenesis.

bioRxiv · Dec 16, 2021Microbiology

Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant

A.-K. Reuschl, L. Thorne, L. Zuliani Alvarez, M. Bouhaddou, K. Obernier, J. Hiatt, M. Soucheray, J. Turner, J. Fabius, G. T. Nguyen, D. Swaney, R. Rosales, K. M. White, P. Aviles, I. T. Kirby, , N. J. Krogan

This study evaluates the efficacy of host-directed therapies against the B.1.1.7 SARS-CoV-2 variant and finds similar antiviral activity compared to early-lineage SARS-CoV-2.

bioRxiv · Jan 24, 2021 · PreprintMicrobiology