Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
K. Tharp, S. Park, G. A. Timblin, A. Richards, J. Berg, N. Twells, N. M. Riley, E. Peltan, D. J. Shon, E. Stevenson, C. K. Tsui, F. Palomba, A. E. Lefebvre, R. Soens, N. Ayad, , V. Weaver
This study shows that the physical properties of the microenvironment influence glycocalyx composition and immune surveillance in vitro using physiologically relevant models.
bioRxiv · Jun 23, 2023 · PreprintCell Biology
S. Silas, H. Carion, K. S. Makarova, E. Laderman, D. S. Godinez, M. Johnson, A. Fossati, D. Swaney, M. Bocek, E. V. Koonin, J. Bondy-Denomy
The paper identifies and characterizes phage accessory genes (AGs) that activate host antiviral immunity, including programmed cell death, and explores their evolutionary implications.
bioRxiv · Apr 6, 2023 · PreprintMicrobiology
A. Pitea, R. Turnham, M. Eckhardt, G. M. Jang, Z. Xu, H. C. Lim, A. Choi, J. Von Dollen, R. S. Levin, J. T. Webber, E. McCarthy, J. Hu, X. Li, L. Che, G. Chan, , J. Gordan
This study identifies how HBV alters PP2A complexes to drive liver cancer signaling, revealing potential therapeutic targets.
bioRxiv · Mar 15, 2023 · PreprintCancer Biology
J. Sherry, L. Dolat, E. MacMahon, D. Swaney, R. Bastidas, J. R. Johnson, R. Valdivia, N. J. Krogan, C. Elwell, J. Engel
This study identifies Dre1, a Chlamydia effector that interacts with dynactin to reposition host organelles during infection, enhancing bacterial fitness.
bioRxiv · Apr 15, 2022 · PreprintMicrobiology
A.-K. Reuschl, L. Thorne, L. Zuliani Alvarez, M. Bouhaddou, K. Obernier, J. Hiatt, M. Soucheray, J. Turner, J. Fabius, G. T. Nguyen, D. Swaney, R. Rosales, K. M. White, P. Aviles, I. T. Kirby, , N. J. Krogan
This study evaluates the efficacy of host-directed therapies against the B.1.1.7 SARS-CoV-2 variant and finds similar antiviral activity compared to early-lineage SARS-CoV-2.
bioRxiv · Jan 24, 2021 · PreprintMicrobiology
P. Finneran, M. Soucheray, C. Wilson, R. Otten, V. Buosi, N. J. Krogan, D. Swaney, D. Theobald, D. Kern
This study reveals the bimodal evolution of Src and Abl kinase substrate specificity using mammalian cell extract as a substrate pool, showing divergent evolutionary paths leading to specific and promiscuous enzymes.
bioRxiv · Aug 12, 2020 · PreprintBiochemistry
K. M. Tharp, R. Higuchi-Sanabria, G. Timblin, B. Ford, C. Garzon-Coral, C. Schneider, J. M. Muncie, C. Stashko, J. Daniele, A. S. Moore, P. Frankino, S. Manoli, H. Shao, A. L. Richards, K.-H. Chen, , V. M. Weaver
The paper shows that adhesion-mediated mechanosignaling activates a mitochondrial stress response through SLC9A1 and HSF1, altering mitochondrial function in aging and cancer.
bioRxiv · Mar 6, 2020Cell Biology
J. M. Budzik, N. E. Garelis, T. Repasy, A. W. Roberts, L. Popov, T. J. Parry, D. Jiminez-Morales, D. Swaney, J. R. Johnson, N. J. Krogan, J. S. Cox
The paper uses proteomic analysis to identify TAX1BP1 as a mediator of autophagy targeting M. tuberculosis during macrophage infection.
bioRxiv · Jan 31, 2019 · PreprintMicrobiology