Author

T. Stephan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:deep learning· 2 Assay:fluorescence / live-cell microscopy· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

S. Jakobs· 5 shared D. Riedel· 3 shared M. Bates· 2 shared A. Hüper· 1 shared A. Przybylski· 1 shared A. R. Cereceda Delgado· 1 shared A. Roesch· 1 shared C. Eggeling· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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5 shared papersCell Biology

S. Jakobs

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments

T. Stephan, S. Stoldt, M. Barbot, T. D. Carney, F. Lange, M. Bates, P. Bou Dib, H. Shcherbata, M. Meinecke, D. Riedel, S. Dennerlein, P. Rehling, S. Jakobs

This study identifies DmMIC10b as the major MIC10 orthologue in Drosophila, showing it polymerizes into cristae-shaping filaments that affect mitochondrial structure and fly lifespan.

bioRxiv · Apr 17, 2023 · PreprintCell Biology

Deep learning enables fast, gentle STED microscopy

V. Ebrahimi, T. Stephan, J. Kim, P. Carravilla, C. Eggeling, S. Jakobs, K. Y. Han

This paper uses deep learning to denoise STED images, reducing photobleaching and photodamage by significantly lowering pixel dwell time.

bioRxiv · Jan 26, 2023Bioengineering

Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain

T. Liu, T. Stephan, P. Chen, J. Chen, D. Riedel, Z. Yang, S. Jakobs, Z. Chen

This paper introduces a new fluorescent marker, PKMO, enabling 3D live-cell STED nanoscopy of mitochondria with improved photostability and reduced phototoxicity, allowing multiplexed imaging of mitochondrial dynamics and interactions.

bioRxiv · May 9, 2022Cell Biology

Optimal Precision and Accuracy in 4Pi-STORM using Dynamic Spline PSF Models

M. Bates, J. Keller-Findeisen, A. Przybylski, A. Hüper, T. Stephan, P. Ilgen, A. R. Cereceda Delgado, E. D'Este, S. Jakobs, S. J. Sahl, S. W. Hell

This paper develops a 4Pi-STORM microscope with dynamic spline PSF models to achieve high 3D resolution and accuracy in single molecule localization microscopy.

bioRxiv · Oct 19, 2021Biophysics

Live-cell STED microscopy of mitochondrial cristae

T. Stephan, A. Roesch, D. Riedel, S. Jakobs

The paper uses STED microscopy to visualize mitochondrial cristae dynamics in living human cells using a Cox8A-SNAP-tag fusion protein.

bioRxiv · May 17, 2019Cell Biology