Structural basis for BIRC6 to balance apoptosis and autophagy
S. Liu, T. Jiang, F. Bu, J. Zhao, G. Wang, G. Yang, J. Kong, Y. Qie, P. Wen, L. Fan, N. Li, N. Gao, X. Qiu
This study reveals the structural basis of BIRC6's role in balancing apoptosis and autophagy by showing its dimeric structure and interactions with Smac/DIABLO, caspase 3, HtrA2, and LC3.
bioRxiv · Dec 10, 2022 · PreprintCell Biology