Author

F. Bu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Biophysics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:deep learning· 2 Assay:structural biology· 2 Research Focus:benchmarking· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1

Frequent Co-Authors

H. Liu· 2 shared Y. Feng· 2 shared Y. Fu· 2 shared A. J. Simpkin· 1 shared A. M. Berry· 1 shared D. J. Rigden· 1 shared E. Wang· 1 shared E. Westhof· 1 shared

Activity by Year

2022-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersEvolutionary Biology

H. Liu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Assessment of three-dimensional RNA structure prediction in CASP15

R. Das, R. C. Kretsch, A. J. Simpkin, T. Mulvaney, P. Pham, R. Rangan, F. Bu, R. M. Keegan, M. Topf, D. J. Rigden, Z. Miao, E. Westhof

This paper evaluates RNA 3D structure prediction methods in CASP15, finding that non-deep learning groups outperformed deep learning models, with challenges in fine details and model ranking.

bioRxiv · Apr 25, 2023Biophysics

Comparative Phylogenomics and Phylotranscriptomics Provide Insights into the Genetic Complexity of Nitrogen Fixing Root Nodule Symbiosis

Y. Zhang, Y. Fu, W. Xian, X. Li, Y. Feng, F. Bu, Y. Shi, S. Chen, R. v. Velzen, A. M. Berry, M. G. Salgado, H. Liu, T. Yi, P. Fournier, N. Alloisio, , S. Cheng

The paper uses phylogenomic and phylotranscriptomic analyses to study the evolution of nitrogen-fixing root nodule symbiosis across the Nitrogen-Fixing Nodulation Clade, finding no convergence at the amino acid level and highlighting the role of NIN as a master regulator.

bioRxiv · Apr 3, 2023Evolutionary Biology

HCC-1 accelerates atherosclerosis by inducing endothelial cells and macrophages pyroptosis and serves as an early diagnostic biomarker

F. Bu, J. Wang, Q. Zhang, X. Lin, R. Zhang, L. H. Bai, J. Chen, Y. Hua, M. Huang, Y. Huang, H. Wang, X.-M. Hu, L. Zheng, Q. Wang

This study shows HCC-1 promotes atherosclerosis by inducing pyroptosis in endothelial cells and macrophages and suggests it as an early diagnostic biomarker.

bioRxiv · Mar 22, 2023Cell Biology

High-throughput screening of functional neo-antigens and their specific TCRs via the Jurkat reporter system combine with droplet microfluidics

Y. Li, J. Qi, Y. Liu, Y. Zheng, H. Zhu, Y. Zang, X. Guan, S. Xie, H. Zhao, Y. Fu, H. Xiang, W. Zhang, H. Chen, H. Liu, Y. Zhao, , Y. Liu

The paper develops a high-throughput platform for screening functional neo-antigens and their specific TCRs using droplet microfluidics and DNA barcoding.

bioRxiv · Feb 20, 2023 · PreprintBioengineering

Structural basis for BIRC6 to balance apoptosis and autophagy

S. Liu, T. Jiang, F. Bu, J. Zhao, G. Wang, G. Yang, J. Kong, Y. Qie, P. Wen, L. Fan, N. Li, N. Gao, X. Qiu

This study reveals the structural basis of BIRC6's role in balancing apoptosis and autophagy by showing its dimeric structure and interactions with Smac/DIABLO, caspase 3, HtrA2, and LC3.

bioRxiv · Dec 10, 2022 · PreprintCell Biology