Author

P.-R. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

C. Deng· 1 shared C. R. Voolstra· 1 shared C. Xu· 1 shared C.-C. Chien· 1 shared G.-S. Chiu· 1 shared H. Long· 1 shared H. Luo· 1 shared H.-C. Cheng· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperEcology

C. Deng

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A standalone reverse dissimilatory sulfite reductase (rDsr) pathway enables sulfur oxidation under oxygen limitation

X. Lin, W.-Q. Zhao, X. Feng, C. Xu, P.-R. Chen, X. Wang, C. Deng, H. Long, C. R. Voolstra, W. B. Whitman, Y. Zhao, P.-F. Xia, H. Luo

This study shows that the reverse dissimilatory sulfite reductase (rDsr) pathway can independently oxidize thiosulfate under low oxygen conditions, supporting its ecological role in marine sediments.

bioRxiv · Jun 14, 2024 · PreprintEcology

Hydrogen Sulfide Coordinates Glucose Metabolism Switch through Destabilizing Tetrameric Pyruvate Kinase M2

R.-H. Wang, P.-R. Chen, Y.-T. Chen, Y.-C. Chen, Y.-H. Chu, C.-C. Chien, P.-C. Chien, S.-Y. Lo, Z.-L. Wang, M.-C. Tsou, S.-Y. Chen, G.-S. Chiu, W.-L. Chen, Y.-H. Wu, L. Wang, , K.-T. Lin

This study shows hydrogen sulfide destabilizes PKM2 tetramer through sulfhydration at cysteine 326, rewiring glucose metabolism and inhibiting tumor growth.

bioRxiv · Sep 2, 2023Cancer Biology