Author

R. H. Mak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Gonzalez· 2 shared H. M. Hoffman· 2 shared P. Zhou· 2 shared R. Zheng· 2 shared S. Hao· 2 shared W. W. Cheung· 2 shared Z. Wang· 2 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersPhysiology

A. Gonzalez

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2 papers

Recent·Most cited

PhysiologybioRxivFeb 5, 2021

Targeting interleukin-1 for reversing fat browning and muscle wasting in infantile nephropathic cystinosis

W. W. Cheung, S. Hao, R. Zheng…·R. H. Mak

This paper shows that anakinra, an IL-1 receptor antagonist, reduces fat browning and muscle wasting in Ctns-/- mice, suggesting it could treat cachexia in infantile nephropathic cystinosis.

DOI 10.1002/jcsm.12744

mouseproteomics

𝕏 PostBluesky

PhysiologybioRxivFeb 5, 2021

The role of IL-1 in adipose browning and muscle wasting in CKD-associated cachexia

W. W. Cheung, R. Zheng, S. Hao…·R. H. Mak

This study shows that blocking IL-1 receptor reduces adipose browning and muscle wasting in CKD-associated cachexia in mice.

DOI 10.1038/s41598-021-94565-y

mousebulk RNA-seq

𝕏 PostBluesky