Author

U. De

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

W. Zhang· 3 shared A. Bruijnzeel· 1 shared A. C. Lynch· 1 shared A. Fagan· 1 shared A. Riva· 1 shared A. Scala· 1 shared A. Sobh· 1 shared B. Freeman· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCancer Biology

W. Zhang

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Author profile →

3 papers

Recent·Most cited

AB-free kava enhances resilience against the adverse health effects of tobacco smoke in mice

T. Bian, A. C. Lynch, K. Ballas, J. Mamallapalli, B. Freeman, A. Scala, Y. Wang, H. Trabouls, R. k. Chellian, A. Fagan, Z. Tang, H. Ding, U. De, K. M. Fredenburg, Z. Huo, , C. Xing

This study evaluates AB-free kava's effects on tobacco smoke-exposed mice, showing it mitigates health deficits with safety, suggesting potential for reducing tobacco-related harm.

bioRxiv · Jun 25, 2024 · PreprintPharmacology & Toxicology

KDM6A Regulates Immune Response Genes in Multiple Myeloma

D. Dupere-Richer, A. Riva, S. Maji, B. G. Barwick, H. Casella, A. Sobh, G. Quickstad, J. Li, u. de, C. Piper, M. Kulis, T. Ezponda, I. Martin-Subero, G. Tonon, W. Zhang, , J. D. Licht

This study shows KDM6A regulates immune response genes in multiple myeloma by activating NLRC5 and CIITA, and its loss reduces MHC expression, which can be reversed by HDAC3 inhibitors.

bioRxiv · Feb 12, 2024Cancer Biology

Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibits small-cell lung cancer growth without causing on-target toxicities in mice

S. KHAN, P. Kellish, N. Connis, D. Thummuri, J. Wiegand, P. Zhang, X. Zhang, V. Budamagunta, N. Hua, Y. Yang, U. De, L. Jin, W. Zhang, G. Zheng, R. Hromas, , D. Zhou

bioRxiv · Sep 12, 2022Cancer Biology