R. M. Parton

This paper introduces Deep3DSIM, an upright 3D-SIM system with adaptive optics for deep tissue imaging, achieving high-quality imaging up to 130 micrometers in Drosophila brain.

The paper systematically analyzes YFP gene traps in Drosophila to show widespread discordance between mRNA and protein expression in the nervous system, revealing common post-transcriptional regulation.

The paper quantifies SARS-CoV-2 RNA molecules using smFISH, revealing genomic RNA stability, cell-to-cell replication variability, and slower replication kinetics for the B.1.1.7 variant compared to the Victoria strain.

The paper introduces Microscope-Cockpit, a Python-based GUI for controlling bespoke microscopes, enabling efficient specimen navigation and hardware integration through open-source tools.

The paper introduces wavefront-sensorless adaptive optics for a laser-free spinning disk confocal microscope, improving signal, contrast, and resolution by correcting specimen-induced aberrations.

The paper describes a low-cost, 3D-printed automated fluorescence imaging system for teaching and outreach, demonstrating its multimodal imaging capabilities and open-source design.

The paper introduces cryoSIM, a super-resolution 3D fluorescence microscope for cryo-imaging that can be replicated with off-the-shelf components and open-source software.

IsoSense improves sensorless adaptive optics by using structured illumination to enhance spatial frequencies for reliable wavefront sensing in microscopy.