R. Ramirez

Acylation of MLKL impacts its function in necroptosis

This study identifies acylation sites on MLKL and shows that acylation at specific cysteines affects its membrane interaction and necroptosis activity.

Characterization of a KDM5 Small Molecule Inhibitor with Antiviral Activity against Hepatitis B Virus

This study identifies a KDM5 inhibitor with anti-HBV activity in vitro but not in vivo, highlighting challenges in translating epigenetic therapies to viral infections.

FoxP3 can fold into two distinct dimerization states with divergent functional implications for T cell homeostasis

This study shows FoxP3 can form two dimerization states, with head-to-head dimerization supporting function and swap-dimerization impairing it.

Comparative Multiomic Analysis Reveals Low T Cell Infiltration as the Primary Feature of Tobacco Use in HPV(+) Oropharyngeal Cancer

This study identifies low T cell infiltration as a key feature of tobacco use in HPV-positive oropharyngeal cancer, linked to worse outcomes.