Author

S. Chugh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Chalk· 1 shared A. G. Kulasekararaj· 1 shared A. Goodrum· 1 shared A. Javorsky· 1 shared A. M. Chinnaiyan· 1 shared A. Pathak· 1 shared A. Sett· 1 shared A. Unnikrishnan· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperCancer Biology

A. Chalk

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Author profile →

4 papers

Recent·Most cited

Dysregulated expression of Hoxa1 isoforms in hematopoietic stem and progenitor cells causes myelodysplastic syndromes.

S. Y. Tan, C. Joseph, M. L. Sobah, A. Chalk, K. Schleibs, S. Lee, G. Tjin, S. Chugh, X. Mo, C. Grace, J. Q. Truong, M. F. Smeets, K. Rice, M. Parker, A. Unnikrishnan, , L. Purton

This study shows that dysregulated Hoxa1 isoforms in hematopoietic stem and progenitor cells cause myelodysplastic syndromes and provide mouse models for disease progression.

bioRxiv · Apr 24, 2023 · PreprintCancer Biology

Acinetobacter baumannii represses type VI secretion system through an Mn2+-dependent sRNA-mediated regulation

S. Bhowmik, A. Pathak, K. Devnath, A. Sett, S. Pandey, N. Jyoti, T. Bhando, J. Akhter, S. Chugh, R. Singh, T. K. Sharma, R. Pathania

This study identifies an Mn2+-dependent small RNA-mediated regulation of T6SS in A. baumannii, revealing how Mn2+ influences sRNA binding to repress T6SS.

bioRxiv · Jul 30, 2022 · PreprintMicrobiology

Structural insight into tanapoxvirus mediated inhibition of apoptosis

C. D. Suraweera, M. I. Anasir, S. Chugh, A. Javorsky, R. E. Impey, M. Hasan Zadeh, T. P. Soares da Costa, M. G. Hinds, M. Kvansakul

This study determines the crystal structures of TANV16L bound to Bax, Bim, and Puma BH3, revealing its mechanism of inhibiting apoptosis by adopting monomeric and dimeric forms while maintaining the canonical ligand binding groove.

The FEBS Journal · May 31, 2020Peer-reviewedMicrobiology

An Essential Role for Argonaute 2 in EGFR-KRAS Signaling in Pancreatic Cancer Development

S. Shankar, J. Tien, R. F. Siebenaler, S. Chugh, V. L. Dommeti, S. Zelenka-Wang, J. Waninger, K. M. Juckette, A. Xu, X.-M. Wang, M. Mody, S. Eyunni, A. Goodrum, G. Tsaloff, Y. Zhang, , A. M. Chinnaiyan

This study shows AGO2 is required for pancreatic cancer progression but not initiation, with its role dependent on mutant KRAS and EGFR signaling.

bioRxiv · Aug 1, 2019Cancer Biology