Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in Myc-driven Medulloblastoma
B. L. Veo, E. Danis, A. Pierce, D. Wang, S. Fosmire, K. D. Sullivan, M. Joshi, S. Khanal, N. Dahl, S. Karam, N. Serkova, S. Venkataraman, R. Vibhakar
This study identifies CDK7 as a therapeutic target in Myc-driven medulloblastoma, showing that its inhibition sensitizes tumors to radiation.
Cell Reports · Apr 1, 2021Peer-reviewedCancer Biology